Reference: AIPREKPPC8 Start date: 21/02/2025 0:00:00 Expiration Date: 12/03/2025 23:59:00 The group led by Iván Plaza-Menacho is looking for a PhD student position focused on the structure, function and pharmacology of protein kinases implicated in...
  • Reference: AIPREKPPC8
  • Start date: 21/02/2025 0:00:00
  • Expiration Date: 12/03/2025 23:59:00

The group led by Iván Plaza-Menacho is looking for a PhD student position focused on the structure, function and pharmacology of protein kinases implicated in cancer. We are looking for a highly motivated candidate with a background in cell biology and tissue culture, biochemistry and structural biology.

Selection Criteria

  • Biochemistry, Biology or related areas.
  • Proven experience in molecular biology, protein expression-purification, protein biochemistry as well as exposure to structural biology.
  • Technical knowledge and experience in other complementary disciplines such as cellular biology and signaling will be very positively valued.
  • Good lab technical skills and abilities, versatile and multifaceted researcher able to multitask.
  • Technical skills:
  • Molecular biology (cloning and mutagenesis).
  • Tissue culture (insect cells and cancer cell lines).
  • Protein expression in different heterologous systems (bacterial and/or insect cells using baculovirus) and purification affinity, size-exclusion and ionic-exchange chromatography.
  • Protein biochemistry (WBs and phosphorylation assays) and biophysics (enzymatic assays, DSF, calorimetry, AUC).
  • Good level of English speaking and writing.
  • Detailed documentation of all experimental work is essential.
  • Good communication and Team work skills.

The CNIO Offers

  • The opportunity to be part of a Cancer Research Centre of excellence.
  • Competitive salary.
  • An energetic working environment.
  • Contract linked to a project.

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